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. 2006 Sep 27;399(Pt 2):225–229. doi: 10.1042/BJ20060425

Table 1. Kinetic and thermodynamic parameters for the binding and inhibition of bacterial ART activity by HNP1.

Variable NAD+ substrate: uncompetitive inhibition Variable eEF2 substrate: competitive inhibition
Toxin IC50 (μM) Ki (μM) Kd (μM) Ki (μM)
DT 11.1±2.6  7.3±1.7  6.8±1.2 6.7±1.1
ETA 19.2±6.5 13.3±0.9 21.5±2.1 5.3±0.4