TABLE 2.
BG content of intravenous antimicrobialsa
| Medication | Concn of BG (pg/ml) at the:
|
||
|---|---|---|---|
| RVC | DIC | MPC | |
| Colistin | 4,348 | 627b | <4 |
| Ertapenem | 3,472 | 166 | <32 |
| Cefazolin (vials) | 2,054 | 67 | <4 |
| Trimethoprim-sulfamethoxazole | 1,187 | <32 | <8 |
| Cefotaxime | 560 | 153 | <8 |
| Cefepime | 425 | 106 | <8 |
| Ampicillin-sulbactam | 519c | <4 | <8 |
| Azithromycin | <62,500 | <1,250 | <8 |
| Pentamidine | <5,000 | <2,187 | <4 |
| Tobramycin | <1,600 | <4 | <4 |
| Liposomal amphotericin B | <1,600 | <16 | 4 |
| Vancomycin | <800 | <32 | <4 |
| Oxacillin | <800 | 4 | <4 |
| Itraconazole | <600 | 23 | <4 |
| Doxycycline | <600 | <16 | <4 |
| Quinupristin-dalfopristin | <600 | 5 | <4 |
| Nafcillin | <400 | 22 | <4 |
| Rifampin | <400 | 23 | <4 |
| Chloramphenicol | <200 | 39 | 5 |
| Amphotericin B deoxycholate | <200 | NT | NT |
| Daptomycin | <200 | Optical artifact | 4 |
| Voriconazole | <200 | 14 | <4 |
| Amikacin | <80 | NT | NT |
| Aztreonam | <80 | 14 | <4 |
| Caspofungin | <80 | NT | NT |
| Cefuroxime | <80 | 21 | <4 |
| Erythromycin | <80 | NT | NT |
| Gentamicin | <80 | NT | NT |
| Imipenem | <80 | NT | NT |
| Piperacillin-tazobactam | <80 | <16 | <8 |
| Ticarcillin-clavulanate | <80 | 13 | 8 |
| Ampicillin | <40 | NT | NT |
| Cefazolin (bag) | <32 | <32 | <4 |
| Cefoxitin | <40 | NT | NT |
| Ceftazidime | <40 | NT | NT |
| Ceftriaxone | <40 | NT | NT |
| Ciprofloxacin | <40 | <4 | <4 |
| Clindamycin | <40 | NT | NT |
| Fluconazole | <40 | <4 | <4 |
| Levofloxacin | <40 | <4 | <4 |
| Linezolid | <40 | <16 | <4 |
| Meropenem | <40 | NT | NT |
| Metronidazole | <40 | 6 | <4 |
| Penicillin G | <40 | <16 | <4 |
| Tigecycline | <16 | NT | NT |
Drugs were ordered according to their BG reactivity. Antimicrobials that tested positive are listed first, followed by antimicrobials that inhibited the BG assay at the RVC. For positive or highly inhibitory assay results, the value provided is the average of three determinations. NT, not tested.
Only one vial was reactive; the other two lots inhibited the reaction at dilutions up to 1:500 (<1,563 pg/ml of BG).
Only one of three vials was reactive; the other two lots inhibited the reaction at dilutions up to 1:100 (<313 pg/ml of BG).