Skip to main content
British Medical Journal logoLink to British Medical Journal
. 1974 Oct 5;4(5935):16–18. doi: 10.1136/bmj.4.5935.16

Controlled Clinical Trial of Mepiprazole in Irritable Bowel Syndrome

G Dotevall, E Groll
PMCID: PMC1612118  PMID: 4609545

Abstract

The effect of a new tranquillizer, mepiprazole, in the treatment of the irritable bowel syndrome has been studied in a double-blind cross-over trial in 19 patients. After examination to exclude organic disease the patients were followed up over two treatment periods of four weeks each under either placebo or the active principle, each patient being his own control. The results indicated that the drug had a beneficial effect (P < 0·05) provided that it was given for a period of at least three weeks.

Full text

PDF
18

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CHAUDHARY N. A., TRUELOVE S. C. The irritable colon syndrome. A study of the clinical features, predisposing causes, and prognosis in 130 cases. Q J Med. 1962 Jul;31:307–322. [PubMed] [Google Scholar]
  2. KIRSNER J. B., PALMER W. L. The irritable colon. Gastroenterology. 1958 Mar;34(3):491–501. [PubMed] [Google Scholar]
  3. Wolf S. Stress and the gut. Gastroenterology. 1967 Feb;52(2):288–289. [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES