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Mean Fold Increase above the Control Level of Activities of Pro-Oncotic and Pro-Apoptotic Enzymes in Keratinocytes Incubated for 24 Hours with IgGs from 30 PV Patients versus Normal IgG (Control)
| Cell death enzyme | First group (19 PV patients) | Second group (11 PV patients) | P (between two groups) |
|---|---|---|---|
| Calpain | 12.1 ± 2.3 | 20.0 ± 1.9 | <0.05 |
| Caspase 3 | 19.3 ± 2.3 | 11.8 ± 1.9 | <0.05 |
| Caspase 8 | 19.1 ± 1.8 | 10.34 ± 1.4 | <0.05 |
| Caspase 9 | 10.2 ± 1.9 | 8.89 ± 1.7 | >0.05 |
