Table III.

Association of defect size with delay from initial evaluation

Duration of delay from initial evaluation	Number of subjects	Coefficient β (SE)	Size ratio (CI)a	p-value
<1 mo	41	0	1	(Reference)
1–3 mo	35	−0.06 (0.22)	0.9 (0.6–1.4)	0.8
3–6 mo	41	−0.10 (0.21)	0.9 (0.6–1.4)	0.6
6–12 mo	39	0.06 (0.20)	1.1 (0.7–1.6)	0.8
More than 1 y	40	0.70 (0.22)	2.0 (1.3–3.1)	0.0016
Unknown	23

Coefficients are standardized with anatomic site, age, histologic subtype, and gender controlled in analysis. The dependent variable was the log of defect size (cm²). p-value is based on F test.

^aSize ratio is defined by using e^β, e.g. e^0.70 =2.0, which clinically represents a doubling of defect size.

CI, confidence interval.