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. 2003 Jun 15;111(12):1905–1912. doi: 10.1172/JCI17247

Figure 4.

Figure 4

Capsule expression and collagen-binding activity of a mouse-passaged serotype M1 S. pyogenes. Transmission electron microscopic images show M1 S. pyogenes strain KTL3 grown directly in medium (a) or cultivated from blood of infected mice (b). (c) A highly encapsulated mouse-passaged M18 strain 87282. (d) Collagen-binding activities are shown for M18 and M1 isolates grown in medium (light gray bars) or cultivated from blood of infected mice (dark gray bars). Collagen binding is expressed as a ratio of bound radiolabeled CIV to streptococci. Bars, 0.25 μm (a–c).