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Statistical distribution of idealization estimates. Irreversible kinetics with uniform steps with SNR 5 and CVJ = 0 (A1 and B1) or 10% (A2 and B2); 1000 data sets were idealized individually. (A) The estimates of μJ, σJ, and σM have Gaussian distribution. (B) There is good correlation between the estimated and the true values, for μJ and for kF, but poor correlation for σJ. Ideally, all estimates should fall on the diagonal line, as observed for zero step variability (B1).
