Table 2.
Functional categories | ANU265 | B. subtilis* | ||
Cell envelope and cellular processes | ||||
Cell wall | 17 | (1.9) | 93 | (3.9) |
Transport/binding proteins and lipoproteins | 184 | (20.0) | 381 | (16.0) |
Sensors (signal transduction) | 21 | (2.3) | 38 | (1.6) |
Membrane bioenergetics (electron transport and ATP synthase) | 49 | (5.3) | 78 | (3.3) |
Surface polysaccharides biosynthesis and export | 25 | (2.7) | 16 | (0.7) |
Sporulation | 1 | (0.1) | 139 | (5.8) |
Germination/transformation | 0 | 43 | (1.8) | |
Mobility and chemotaxis | 26 | (2.8) | 55 | (2.3) |
Cell division | 5 | (0.5) | 21 | (0.9) |
Protein secretion | 13 | (1.4) | 18 | (0.8) |
Chaperones/heat-shock proteins | 12 | (1.3) | 15 | (0.6) |
Cell death | 8 | (0.9) | 5 | (0.2) |
Intermediary metabolism | ||||
Carbohydrates and related molecules | 69 | (7.5) | 261 | (11.0) |
Amino acids and related molecules | 91 | (9.9) | 202 | (8.5) |
Nucleotides and nucleic acids | 11 | (1.2) | 83 | (3.5) |
Lipids | 19 | (2.1) | 77 | (3.2) |
Cofactors/prosthetic groups | 37 | (4.0) | 99 | (4.2) |
Phosphate | 3 | (0.3) | 9 | (0.4) |
Opine-like compounds | 8 | (0.9) | 3 | (0.1) |
Sulphur | 2 | (0.2) | 8 | (0.3) |
Information pathways | ||||
DNA replication, restriction, modification and repair | 26 | (2.8) | 61 | (2.6) |
DNA segregation, recombination and transfer | 10 | (1.1) | 27 | (1.1) |
RNA synthesis and modification | 19 | (2.1) | 50 | (2.1) |
Protein synthesis and modification | 63 | (6.8) | 123 | (5.2) |
Regulatory functions | 68 | (7.4) | 213 | (8.9) |
Other categories | ||||
Adaptation to atypical conditions and protection | 27 | (2.9) | 147 | (6.2) |
Transposon-related functions | 51 | (5.5) | 10 | (0.4) |
Phage-related functions | 5 | (0.5) | 83 | (3.5) |
Miscellaneous | 52 | (5.6) | 21 | (0.9) |
Total | 922 | (100) | 2,379 | (100) |
*The functional classification of the B. subtilis protein-coding genes was adapted from Kunst et al. [29]. The number of sequences and of genes in each category is listed for ANU265 and B. subtilis, respectively. The percent of the putatively identified genes devoted to each functional group is indicated in brackets.