Table 2.
Telomere length | Normal lobules (n = 24) | Normal lactiferous ducts (n = 15) | Male breast (n = 5) | Normal pediatric lobules (n = 7) | Fibrocystic changes (n = 10) | DCIS (n = 23) | LCIS (n = 6) | Invasive mammary carcinoma (n = 114) |
---|---|---|---|---|---|---|---|---|
Very short | 0 | 0 | 0 | 0 | 1 | 11 | 1 | 60 (52.5%) |
Short | 10 | 0 | 0 | 2* | 1 | 7 | 4 | 20 (17.5%) |
Normal | 8 | 15 | 5† | 5 | 8 | 4 | 1 | 24 (21%) |
Long | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 (5%) |
Heterogeneous | 6 | 0 | 0 | 0 | 0 | 1 | 0 | 4 (4%) |
Luminal shortening was focal in these cases.
Focal luminal telomere shortening was seen in a lobule of a male breast with gynecomastia.