Table 1.
Transplanted heart | Day harvested after transplant | Number of vessels with NI > 10% | Cumulative NI |
---|---|---|---|
C3H male | 59 | 8/10 | 46% |
C3H male | 61 | 8/12 | 39% |
C3H male | 69 | 14/21 | 28% |
C3H male | 62 | 18/20 | 55% |
C3H male | 61 | 5/16 | 12.5% |
C3H female | 65 | 1/7 | 6% |
C3H female | 76 | 1/8 | 6% |
C3H female | 56 | 0/12 | < 5% |
Two to three elastin-stained sections of each heart graft were analyzed by computer-assisted image analysis for both the number of vessels with neointimal index (NI) of > 10% and the cumulative score for all vessels computed as outlined in Materials and Methods. Both the numbers of involved vessels and the overall NI were significantly greater in the male versus the female heart grafts (P < 0.05).