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Cyclophilin (CyPA) Demonstrates Biphasic Effects upon Cultured Endothelial Cells: Effect of in Vitro CyPA Treatment of HUVECs upon Cell Proliferation and Migration
| CyPA (ng/ml)
|
||||||
|---|---|---|---|---|---|---|
| 0 | 1 | 10 | 100 | 1000 | 2000 | |
| Proliferating cells (%) | 18.6 (8.2) | 20.6 (0.9) | 32.7 (1.2)* | 19.7 (1.5) | 9.0 (1.0) | 7.0 (1.2) |
| Migrated cell number | 48 (7) | 95 (6)* | 181 (18)* | 114 (15) | 58 (7) | 36 (6) |
All values are mean (SEM).
P < 0.05 versus no treatment (basal conditions).
