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Dose response of the effects of dexamethasone. Dexamethasone at doses indicated was administered to BALB/c mice 24 hours before receiving 108 Jurkat cells treated with etoposide to induce apoptosis. DNA (A) and LDH (B) were measured as described. Results are reported as means (±SD) for four mice for controls and dexamethasone at 1 mg and 2.5 mg, and two mice for dexamethasone at 0.1 mg and 0.5 mg. Values differing from control by P < 0.05 are indicated by an asterisk.
