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. 2005 Nov 7;147(1):36–44. doi: 10.1038/sj.bjp.0706433

Figure 1.

Figure 1

Genistein reduces the whole-cell If current. (a) If current was elicited every 6 s by a 2-s hyperpolarizing step to −75 mV from a holding potential of −35 mV. Sample traces recorded in control solution (1), during superfusion of genistein (50 μM, 2) and after washout (3) are shown. (b) Time course of If amplitude at −75 mV; the horizontal bar indicates the time of genistein superfusion (gen); the calculated inhibition was 24.2%. Continuous line represents the single exponential fitting of the onset (τ=17.3 s) and removal (τ=27.4 s) of the block.