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Interactions of losartan and angiotensin II on the PV electrical activity. (a) Angiotensin II (100 nM) only slightly increased the spontaneous activity in the presence of 10 μM losartan. (b) In the presence of angiotensin II (100 nM), 10 μM losartan inhibited the spontaneous activity of the PV cardiomyocytes.
