Figure 7. Effects of paionin-1 on the binding of the uPA–PAI-1 complex to endocytosis receptors.

(A) Effects of biotin–paionin-1 on the binding of ¹²⁵I-uPA–PAI-1 (●) and ¹²⁵I-RAP (○) to immobilized LRP-1A. Results are means±S.D. for at least two independent experiments. (B) Effects of biotin–paionin-1 on degradation of ¹²⁵I-uPA–PAI-1 (●) and ¹²⁵I-RAP (○) by U937 cells. results are means±S.D. for one experiment performed in duplicate, representative of three independent experiments.