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(A) Mice from four different genotypes (n=8–10 per genotype) were given an i.p. (intraperitoneal) injection of 600 mg of APAP/kg and observed for 70 h. (B) WT and SOD1−/− mice (n=6) were given an i.p. injection of 1200 mg of APAP/kg and observed for 24 h. Values are means±S.E.M.; and ‘#’ indicates the genotype effect (P<0.05).
