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. 2006 Oct 13;399(Pt 3):455–461. doi: 10.1042/BJ20060784

Figure 6. Hepatic microsomal activities or concentrations of CYP2E1 and UGT1A6 in WT and SOD1−/− mice treated with PBS or 600 mg of APAP/kg.

Figure 6

(A) CYP2E1 activity. (B) CYP2E1 protein. (C) UGT1A6 activity. Mice were killed at 5 h after the injection of PBS or APAP. In (A) and (C), values are means±S.E.M. (n=5); ‘#’ indicates the genotype effect (P<0.05) within the same treatment. (B) is representative of three independent experiments, and the Western-blot analysis was conducted using SDS/PAGE (12% gel), a primary rabbit polyclonal anti-CYP2E1 antibody and a secondary goat anti-rabbit IgG antibody.