Fig. 2.

EB1089 decreases mammary epithelial cell proliferation in LH-overexpressing mice. EB1089 or vehicle was injected subcutaneously into LH-expressing female mice for 2 weeks after weaning. At 5 weeks of age, the mammary glands from vehicle (A) and EB1089 (B) treated animals were assessed for proliferation using BrdU labeling analysis (400× magnification). (C) EB1089 treated animals exhibited 35% fewer BrdU positive mammary epithelial cells than vehicle treated controls (*P<0.05).