Figure 7. COX-2 and iNOS immunostaining of tissue sections obtained from wild-type and Cyld^–/–mice 7 days after the first, second, and third cycles of DSS treatment.

Numerous COX-2–positive cells were observed in the epithelium, and iNOS-positive cells were observed within broadly based inflammatory infiltrating cells, of the adenomatous tissue of Cyld^–/– mice. Arrowheads indicate positively stained cells. Magnification, ×50.