Figure 5.

Effect of increasing doses of rimonabant (mg kg⁻¹) on neuronal counts 7 days after reperfusion in the CA₁ region of the hippocampus of sham-operated or ischemic gerbils. Rimonabant was given i.p. 5 min after recirculation either alone or with capsazepine (CPZ) (0.01 mg kg⁻¹) s.c. 15 min before bilateral carotid arteries occlusion. Each column represents the mean (±s.e.m.) of five hippocampal sections from the same coronal plane for each animal. n=5 for each group. ^aP<0.001 compared with sham-operated animals; ^bP<0.001 compared with vehicle; ^cP<0.001 compared with rimonabant 0.25 and 0.5 mg kg^–1; ^dP<0.001 compared with corresponding rimonabant alone (one-way ANOVA followed by Tukey's test).