Figure 3.

(a) Effects of NalBzoH in CHO/DOR cells. Concentration-dependent stimulation of [³⁵S]GTPγS binding by NalBzoH and other opioid receptor ligands. Values are reported as percent of basal activity and are the mean±s.e.m. of 3–6 determinations. (b) Antagonism of NalBzoH- and DPDPE-stimulated [³⁵S]GTPγS binding by NTI. Values indicate the percent of the stimulatory effect induced by either NalBzoH (100 nM) or DPDPE (100 nM) at each concentration of NTI and are the mean±s.e.m. of three determinations. (c) Concentration-dependent inhibition of FSK-stimulated cyclic AMP accumulation by NalBzoH and DPDPE. Values are reported as percent of control activity (vehicle) and are the mean±s.e.m. of three determinations.