(a, b) Average baroreflex curves generated before and during the first, second, and third hour after ADM (1 fmol) was microinjected into the RVLM (a, n=6) or outside of RVLM (b, n=4). (c, d) Average baroreflex curves generated before and during the first hour after 0.1 fmol ADM (a, n=6) or saline (b, n=4) was microinjected into the RVLM. Insets, average gains of baroreflex control of HR as a function of MAP. Symbols represent the upper plateau, set-point, and lower plateau of baroreflex curves, respectively. *P<0.05 and **P<0.01 versus measurements before microinjections.