Average baroreflex curves generated before and during the first hour after 0.1 fmol ADM22–52 (a, n=4) or 1 fmol ADM22–52 (b, n=6) was microinjected into the RVLM. Insets, average gains of baroreflex control of HR as a function of MAP. Symbols represent the upper plateau, set-point, and lower plateau of baroreflex curves, respectively. *P<0.05 versus measurements before microinjections.