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. 2006 Mar 6;148(2):200–207. doi: 10.1038/sj.bjp.0706717

Figure 3.

Figure 3

Inhibitory effect of trypsin on carbachol-induced contraction in control and DSS-treated rat colon. Typical results of 0.3 μM carbachol-induced contraction for 10 min in control rat colon (a). Trypsin (1 μM) was applied at 5 min after addition of 0.3 μM carbachol in control rat colon (b) and 1 μM carbachol in rat colon treated with DSS for 7 days (c). Analytical results of relaxations in control rat colon and DSS-treated rat colon (treated with DSS for 5 days (day 5) or 7 days (day 7)) (d). AUC of carbachol in the absence of trypsin was considered 100%. Results are expressed as means±s.e.m. of 6–12 experiments. **P<0.01 vs control; $P<0.01 vs day 5; w.o., washing out.