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Inhibitory effect of trypsin on KCl-induced contractions in control and DSS-treated rat colon. Trypsin (1 μM) was applied for 5 min at 5 min after the addition of 20.4 mM KCl in control rat colon (a) and 25.4 mM in DSS-treated rat colon (b). Analytical results of relaxations in control and DSS-treated rat colon (c). Contraction induced by KCl just before addition of trypsin was considered 100%. Results are expressed as means±s.e.m. of 5–6 experiments. **P<0.01; w.o., washing out.
