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Histology results of the heart
| Parameter (unit) | 5/6 NX (n=9) | 5/6 NX+BAY 58-2667 (n=9) | Sham OP (n=10) |
|---|---|---|---|
| Myocyte diameter (μm) |
19.0±4.6** |
14.8±2.3*,† |
12.0±0.9 |
| Media-lumen-ratio |
2.7±1.1* |
1.5±0.8† |
1.5±0.6 |
| Interstitial fibrosis (% of section) |
2.3±1.3 |
1.9±0.8 |
2.4±0.7 |
| Perivascular fibrosis (score) | 2.1±0.5 | 1.8±0.4 | 1.9±0.5 |
Values are given as mean±s.d.
P<0.05/0.001 versus Sham-OP;
P<0.05/0.001 versus Sham-OP;
P<0.05 versus 5/6 NX.
