Figure 2.
Effect of GL and antibothropic serum on thrombus weight after administration of B. jararaca venom in the rat. (a) B. jararaca venom was administered intravenously at the indicated doses and stasis was immediately established for induction of thrombosis, as described in Methods. (b) GL was administered intravenously at the indicated doses 5 min before the induction of thrombosis by venom (100 μg kg−1) combined with stasis. (c) Antibothropic serum was administered intravenously at the indicated doses 5 min before the induction of thrombosis by venom (100 μg kg−1) combined with stasis. (d) GL and antibothropic serum (As) were co-administrated intravenously 5 min before the induction of thrombosis by venom (100 μg kg−1) combined with stasis. Each point represents mean±s.d. of 5–10 animals. Asterisk, P<0.05.