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. 2006 Jun 12;148(6):871–880. doi: 10.1038/sj.bjp.0706795

Figure 7.

Figure 7

The effect of protein kinase inhibitors on the Na,K-ATPase activity response to SNP (a) and 8-pCPT-cGMP (b). Cells were incubated with or without (control) PKG inhibitors H-8 or H-9 or the specific PKA inhibitor H-89 for 15 min. and then SNP or 8-pCPT-cGMP was added for a further 20 min. After this, the cells were homogenized and Na,K-ATPase activity in control and treated samples was measured under identical conditions. The results are the mean±s.e.m. of data from six independent measurements for each experimental group. Statistical comparisons were made by analysis of variance followed by the Bonferroni post hoc multiple comparison tests. *,**and ***indicate significant differences from the control value at P<0.05, P<0.01 and P<0.001, respectively. ≠Indicates a significant difference from SNP-treated samples.