Table 5.

Effect of efflux on MICs of Brucella reference strains for erythromycin and clindamycin.

Brucella	MIC
	Ery	Ery + PAβN	CL	CL + PAβN
B. ab b1	>256	96	>256	96
B. ab b2	0.19	0.0275	3	0.25
B. ab b3	128	64	192	128
B. ab b4	128	64	192	64
B. ab b5	>256	192	128	128
B. ab b6	>256	256	>256	96
B. ab b9	>256	>256	>256	>256
B. mel b1	16	4	24	16
B. mel b2	>256	48	64	12
B. mel b3	256	48	64	32
B. suis b1	1.5	0.75	8	4
B. suis b2	0.125	0.032	3	0.047
B. suis b3	1.5	1.0	24	48
B. suis b4	2	1.5	24	32
B. suis b5	0.094	0.047	6	2
B. canis	0.50	0.094	8	0.50
B. ovis	0.064	<0.016	3	<0.016
B. neo	0.75	0.047	3	0.75
Porpoise	1.5	0.25	16	3
Seal	6	1.5	>256	48
Dolphin	3	0.38	2	0.75

Brucella strains are as listed in Table 1; MIC, minimum inhibitory concentration; Ery, erythromycin; CL, clindamycin; PAβN, efflux inhibitor L-phenylalanine-L-arginine β-naphthylamide; b, biovar; ab, abortus; mel, melitensis; neo, neotomae.