FIG. 2.
Variable locations within the VZV origin-associated region located between reiteration region R4 and ORF 63/70. As there was noted variability between the copy numbers of TA and GA subunits within the origin of replication between virus sequences within a clade, the differences in copy numbers are not shown. Dumas Location refers to the coordinates of the features in the VZV-Dumas IRS copy of the origin of replication; these locations are duplicated in TRS. The nucleotide at each of these variable locations is listed below the coordinates for the four clades examined. Poly-G, Poly-A, and Poly-C refer to homopolymer stretches that have displayed variability in length both between and within clades. A dash (—) indicates that the clade does not have a base at this location due to an insertion or deletion event. The bases listed for clade C are based on the sequence of VZV-8 only. *, VZV-11 from clade D was the only strain reported to contain a G at location 109994.