FIG. 7.

Enhanced expression of VZV gC after treatment with HMBA, RA, and cortisol. After infection with a sonicated VZV inoculum, Mewo cell monolayers were treated with chemicals known to induce the production of PBX and HOX proteins: RA; HMBA; RA and cortisol; HMBA and cortisol; and RA, HMBA, and cortisol. Fresh medium was added at 0 and 48 hpi, along with the treatments, where indicated. Several hundred micrographs of syncytia in each well at each time point were obtained, from which were prepared Z-stack images of four to five representative syncytia. All settings and conditions were identical between these images and Fig. 6. The antibody reagents were the same as in Fig. 5. Green, gC; blue, gE; red, major capsid protein.