Maternal anti-FrCasE immunoglobulins in sera of neonates after placental and/or breastfeeding immunity transfer. Anti-FrCasE IgG1s and IgG2as were assayed in the sera of group I (A and B), group II (C and D), and group III (E and F) animals. (A, C, and E) Concentrations of mothers' anti-FrCasE IgG1s and IgG2as in neonates' sera. The values are the mean ± standard error of the mean (SEM) of the data obtained from two animals sacrificed per time point. The maximal values measured for IgG2as in animals of groups I, II, and III were 195 ± 44.5, 473 ± 57, and 1 ± 0.7 μg/ml, respectively. (B, D, and F). Transfer efficiencies of anti-FrCasE IgG1s and IgG2as. The levels of immunoglobulins were calculated as percentages of immunoglobulins of the same isotype present in the mother's serum at the time of birth. The values are the mean ± SEM of the data obtained from two animals sacrificed per time point.