Table 2.
Odds Ratios and 95% confidence intervals for cervical cancer in relation to -1082 IL-10 alleles in South African cervical cancer cases (CaCx) and controls.
Genotype | CaCx* (n = 197) n (%) | Controls* (n = 182) n (%) | OR1 (95% CI) | OR2 (95% CI) | OR3 (95% CI) |
GG | 29 (15) | 41 (23) | 0.6(0.3–1.0) | 0.6(0.3–1.0) | 0.6(0.3–1.2) |
AA | 88 (45) | 76 (42) | 0.9(0.6–1.5) | 1.0(0.6–1.6) | 1.0(0.6–1.6) |
AG | 80 (41) | 65 (36) | 1.0 | 1.0 | 1.0 |
*Data given as percentages (As there were no differences in the distribution of IL-10 alleles between the mixed race and African groups the data was combined) OR1 = crude odds ratio OR2 = crude OR adjusted for IFN-γ OR3 = adjusted for ethnic group, 5 year age group, years of education, age at first sexual intercourse, number of sexual partners, urban/rural living, number of Pap smears, injectable/oral contraceptive use, smoking, parity, and IFN-γ.