Table 4.
Frequencies (%) of 1. IFN-γ genotype and 2. IL-10 (estimated by the Hardy-Weinberg Equilibrium) alleles in African and mixed race ethnic control groups and other populations.
Allele | South African | #Italian Caucasians | +South-east England | †Manchester, UK | §China | |
African | Mixed race | |||||
1. IFN-γ | (n = 103) | (n = 188) | (n = 363) | |||
+874T/T | 4 | 10 | 21.2 | - | - | - |
+874T/A | 19 | 29 | 46.8 | - | - | - |
+874A/A | 77 | 61 | 32.0 | - | - | - |
2. IL-10 | *(n = 182) | (n = 726) | (n = 152) | (n = 660) | (n = 166) | |
-1082A | 60 | 63 | 47.4 | 51 | 94 | |
-1082G | 40 | 37 | 52.6 | 49 | 6.0 |
*Combined African and mixed race control groups in this study (As there were no differences in the distribution of IL-10 alleles between the two South African ethnic populations, the data was combined to compare allele frequencies to other populations). Data reported by #Poli et al. (2002); +Reynard et al. (2000); †Perrey et al. (1998); §Mok et al. (1998)