Figure 3.

Deletion mutants of RK and their responses to mAb-6D8 and mAb-1C3. (A) The three domains in RK sequence are shown (Top). The seven deletion mutants (I–VII) are shown with the deleted sequences in black. (B) Immunoresponses of the mutants to the antibodies. The mutant proteins were produced in E. coli and tested for their reactivity toward mAb-6D8 and mAb-1C3, as described in Methods; responses are shown by a plus or minus sign.