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Time-dependent inactivation of RK as complexed with mAb-6D8. RK was incubated in the presence of mAb-6D8 (lanes 2–4) as in Methods. The tridecapeptide (Table 1) was absent (lane 2), present throughout (lane 3), or added at the end (lane 4) of the incubation time. After 30 min or 5 h of incubation, RK activity was measured. The results are normalized to the control experiments in the absence of mAb (lane 1).
