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. 2003 Jul;47(7):2242–2248. doi: 10.1128/AAC.47.7.2242-2248.2003

TABLE 2.

Resistance profiles of donor strains and transconjugants

Group and strain MIC (μg/ml)
CIPa AMP CTX GEN SXT SMZ TMP CHL TET
Clinical strains (donors)
    4 64 ≥512 ≥512 ≥512 ≥512 ≥512 ≥128 ≥512 ≥512
    7 128 ≥512 ≥512 ≥512 ≥512 ≥512 ≥128 ≥512 128
    10 128 ≥512 ≥512 ≥512 ≥512 ≥512 ≥128 64 256
    12 128 ≥512 ≥512 ≤1 ≥512 ≥512 ≥128 64 256
    29 64 ≥512 256 ≤1 ≥512 ≥512 ≥128 64 256
    76 ≥256 ≥512 64 ≥512 ≥512 ≥512 ≥128 256 256
Recipient, J53Az 0.008 16 0.03 0.125 0.5 16 0.125 4 1
Transconjugantsb
    4-3 0.25 ≥512 32 8 ≥512 ≥512 ≥128 512 32
    4-59 0.25 ≥512 2 0.125 ≥512 ≥512 ≥128 ≥512 64
    7-24.1 0.125 ≥512 8 2 ≥512 ≥512 ≥128 256 1
    7-24.2 0.125 32 ≤0.03 1 0.5 ≥512 0.125 4 1
    10-5 0.25 32 ≤0.03 0.125 ≥512 ≥512 ≥128 4 64
    10-2 1 ≥512 0.06 0.125 1 ≥512 0.125 4 64
    12-4 1 ≥512 0.06 0.125 1 ≥512 0.125 4 64
    29-11 1 ≥512 0.06 0.125 0.5 ≥512 0.125 4 64
    76-65 2 ≥512 8 128 ≥512 ≥512 ≥128 256 128
a

CIP, ciprofloxacin; AMP, ampicillin; CHL, chloramphenicol; CTX, cefotaxime; GEN, gentamicin; SMZ, sulfamethoxazole; TET, tetracycline; TMP, trimethoprim.

b

qnr is located on different-size plasmids for transconjugants 4-3 and 4-59, as well as 7-24.1 and 7-24.2, whereas qnr is located on the same-size plasmids for 10-5 and 10-2. For another transconjugant, 12-5, the MICs were the same as those for 12-4.