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Pharmacokinetic parameters of Mycograb in mice given a single dose
| Mycograb dose (mg/kg) (sample studied) | Cmax (μg/ml) | AUC0-t (μg · min/ml) | AUC0-∞ (μg · min/ml) | t1/2α (min) | t1/2β (h) | MRT (h) |
|---|---|---|---|---|---|---|
| 2 (serum) | 4.7 | 155 | 157 | 3.75 | 2.34 | 3.17 |
| 10 (serum) | 54.9 | 2,857.4 | 2,859.6 | 7.05 | 2.51 | 2.35 |
| 10 (renal biopsy specimen) | 21.7 | 9,108 | 9,120 | 10.2 | 10.94 | 9.3 |
