Table 3.
Bias | Number of members | Mean disorder (D) value |
Functional categories (GO term [# of occurrences]; description; P' value) |
{P} | 273 | 0.61 | GO:0005737 [55]; cytoplasm (3 × 10-23) |
GO:0007155 [28]; cell adhesion (4 × 10-10) | |||
{C} | 183 | 0.00 | GO:0005515 [37]; protein-binding (2 × 10-4) |
GO:0005509 [35]; calcium-ion binding (3 × 10-15) | |||
GO:0007155 [29]; cell adhesion (5 × 10-16) | |||
GO:0005198 [27]; structural-molecule activity (4 × 10-16) | |||
GO:0046872 [21]; metal-ion binding (4 × 10-3) | |||
GO:0005578 [16]; extracellular matrix (sensu Metazoa) (8 × 10-9) | |||
{GP} | 116 | 0.76 | GO:0005737 [65]; cytoplasm (2 × 10-61) |
GO:0007155 [27]; cell adhesion (2 × 10-19) | |||
GO:0005198 [12]; structural-molecule activity (2 × 10-3) | |||
GO:0005578 [9]; extracellular matrix (sensu Metazoa) (8 × 10-3) | |||
{Q} † | 77 | 0.41 | GO:0005634 [34]; nucleus (3 × 10-8) |
GO:0006355 [21]; DNA-dependent regulation of transcription (1 × 10-4) | |||
{S} | 74 | 0.71 | |
{G} | 70 | 0.40 | GO:0005634 [24]; nucleus (2 × 10-2) |
{E} | 69 | 0.49 | GO:0005198 [10]; structural-molecule activity (1 × 10-3) |
{ED} † | 33 | 0.56 | GO:0005634 [24]; nucleus (1 × 10-11) |
GO:0006355 [14]; DNA-dependent regulation of transcription (6 × 10-5) | |||
{PG} | 32 | 0.75 | |
{QP} † | 30 | 0.52 |
(*) – The CB regions are sorted in decreasing order of abundance. They are denoted by their CB signatures in column #1. Column #2 contains the total number of members in a particular cluster; column #3 is the mean value of D, the disorder fraction of each member; column #4 lists the top five significantly-associated (P' ≤ 0.05, adjusted for multiple hypothesis testing) GO (Gene Ontology terms for the cluster in the format: GO term name [count for GO term]; description of GO term in words. In addition, bias types that are significantly associated with transcription (where we reduced GO categories to just two categories, 'transcription-related' and 'non-transcription-related'), are labelled with a † sign.