Table 5.
Most abundant GO terms for {Q(X)n} CB regions in the fruitfly, mouse, rat and human proteomes *
| Fruitfly (total = 835) | Rat (total = 234) | Mouse (total = 267) | Human (total = 335) | ||||
| Number** | GO term and its description | Number** | GO term and its description | Number** | GO term and its description | Number** | GO term and its description |
| 245 | GO:0005634 ; nucleus | 38 | GO:0005634 ; nucleus | 78 | GO:0005634 ; nucleus | 114 | GO:0005634 ; nucleus |
| 152 | GO:0006357 ; regulation of transcription from RNA polymerase II promoter | 28 | GO:0006355 ; DNA-dependent regulation of transcription | 49 | GO:0006355 ; DNA-dependent regulation of transcription | 68 | GO:0006355 ; DNA-dependent regulation of transcription |
| 137 | GO:0003700 ; transcription factor activity | 15 | GO:0003700 ; transcription factor activity | 36 | GO:0005515 ; protein-binding | 51 | GO:0008270 ; Zinc ion binding |
| 125 | GO:0003677 ; DNA-binding | 6 | GO:0004871 ; signal transducer activity | 31 | GO:0003677 ; DNA-binding | 39 | GO:0003700 ; transcription factor activity |
| 99 | GO:0005515 ; protein-binding | 4 | GO:0030216 ; keratinocyte differentiation | 28 | GO:0008270 ; Zinc ion binding | 35 | GO:0003677 ; DNA-binding |
| 92 | GO:0008270 ; Zinc ion binding | 4 | GO:0001533 ; cornified envelope | 25 | GO:0003700 ; transcription factor activity | 24 | GO:0003676 ; nucleic acid binding |
| 78 | GO:0006355 ; DNA-dependent regulation of transcription | 21 | GO:0005737 ; cytoplasm | 21 | GO:0046872 ; metal-ion binding | ||
| 62 | GO:0005737 ; cytoplasm | 12 | GO:0006350 ; transcription | 20 | GO:0003713 ; transcriptional coactivator activity | ||
| 61 | GO:0007498 ; mesoderm development | 9 | GO:0045944 ; positive regulation of transcription from RNA pol II promoter | 17 | GO:0006350 ; transcription | ||
| 59 | GO:0003677 ; RNA polymerase II transcription factor activity | 9 | GO:0003713 ; transcription coactivator activity | 11 | GO:0006366 ; transcription from RNA pol II promoter | ||
| 57 | GO:0003729 ; mRNA binding | 5 | GO:00016564 ; transcriptional repressor activity | 11 | GO:0004871 ; signal transducer activity | ||
| 53 | GO:0045449 ; regulation of transcription | 5 | GO:00016563 ; transcriptional activator activity | 10 | GO:00016563 ; transcriptional activator activity | ||
| 47 | GO:0009993 ; oogenesis (sensu insecta) | 8 | GO:0003702 ; RNA pol II transcription factor activity | ||||
| 47 | GO:0007398 ; ectoderm development | 6 | GO:0006367 ; Transcription initiation from RNA pol II promoter | ||||
| 47 | GO:0003704 ; specific RNA polymerase II transcription factor activity | ||||||
| 43 | GO:0030528 ; transcription regulatory activity | ||||||
| 41 | GO:0008283 ; cell proliferation | ||||||
| 36 | GO:0003779 ; actin binding | ||||||
| 32 | GO:0007476 ; wing morphogenesis | ||||||
| 30 | GO:0007242 ; intracellular signaling cascade | ||||||
* GO terms common to all four organisms are in bold. Other terms directly associated with 'transcription' or 'nucleic acids' are in italics.
** Number of occurrences of each GO term. For each proteome, the GO terms are sorted in decreasing order of abundance.