Table 6.
Fruitfly | Human | ||||||
Protein folds | Number | Superfamilies | Number | Protein folds | Number | Superfamilies | Number |
a.4, DNA/RNA-binding 3-helical bundle | 53 | a.4.1, Homeodomain-like | 32 | a.4, DNA/RNA-binding 3-helical bundle | 14 | g.50.1, FYVE/PHD Zinc finger | 14 |
g.39, glucocorticoid receptor-like (DNA-binding domain) | 17 | g.39.1, glucocorticoid receptor-like (DNA-binding domain) | 17 | g.50, FYVE/PHD Zinc finger | 11 | a.40.1, calponin homology (CH) domain | 12 |
b.1, Ig-like sandwich | 16 | a.4.5, winged-helix DNA-binding domain | 16 | a.40, CH-domain -like | 9 | d.211.2, plakin repeat | 10 |
d.144, protein kinase -like | 14 | d.144.1, protein kinase -like | 14 | d.211, beta-hairpin-alpha-hairpin repeat (ankyrin & plakin) | 8 | d.144.1, protein kinase -like | 10 |
b.34, SH3-like barrel | 12 | a.123.1, nuclear-receptor ligand-binding domain | 12 | d.144, protein kinase -like | 6 | a.4.1, homeodomain-like | 10 |
a.123, nuclear-receptor ligand-binding domain | 12 |
(*) For each proteome, the most common SCOP domains [18] are listed in decreasing order of abundance. Those that occur in both the Human and Fruitfly lists are highlighted in bold.