Figure 6.
Intracellular [Ca2+]i transients. 1: Highlighted fiber optics overlayed on image of co-culture with neonatal cardiac myocyte (A) and WB F344-derived myocyte expressing GFP (B), intracellularly labeled with indo-1 (scale bar, 100 μm). 2: [Ca2+]i transients recorded at sites A and B. Measured change in [Ca2+]i recorded at sites A and B demonstrated conduction block when the pacing stimulus increased from 1 Hz to 2 Hz. Recorded signals were normalized for fiber optic A and B and offset for display.