TABLE 2.
In vitro susceptibilities of two clinical E. coli isolates and the E. coli ATCC 25922 control strain determined by the broth microdilution methoda
| Antibioticb | MIC (μg/ml)
|
||
|---|---|---|---|
| ATCC 25922 | EC38 | EC44 | |
| AMP | 2 | ≥64 | ≥64 |
| AMX + CLA | ≤0.25 | 16 | 16 |
| CFZ | ≤0.25 | 16 | 16 |
| FOX | ≤0.25 | ≥64 | 8 |
| CFX | ≤0.25 | ≥64 | 16 |
| ATM | ≤0.25 | 8 | 1 |
| CTR | ≤0.25 | ≤0.5 | ≤0.5 |
| CTR + CLA | ≤0.25 | ≤0.25 | ≤0.25 |
| CAZ | ≤0.25 | 4 | 4 |
| CAZ + CLA | ≤0.25 | 2 | 2 |
| CTX | ≤0.25 | 2 | 1 |
| CTX + CLA | ≤0.25 | 1 | 0.25 |
| IPM | ≤0.25 | <0.25 | <0.25 |
| AMK | ≤0.25 | 4 | 2 |
| CIP | 0.06 | 2 | 0.125 |
| TET | ≤1 | ≥64 | 2 |
Strain EC38 had two major bands with pIs of 5.4 and >9, and strain EC44 had one major band with a pI of >9.
AMP, ampicillin; ATM, aztreonam; CTR, ceftriaxone; CAZ, ceftazidime; CTX, cefotaxime; FOX, cefoxitin; AMX, amoxicillin; CFZ, cefazolin; CFX, cefixime; AMK, amikacin; IPM, imipenem; CIP, ciprofloxacin; TET, tetracycline; CLA, clavulanic acid at a fixed concentration 4 μg/ml when tested with ceftazidime, cefotaxime, and ceftriaxone and at a ratio of 2:1 when tested with amoxicillin.