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Ang-1-induced increases in Tie2 and Ang-2 expression in ECs. ECs in ST and WT mice hepatic veins and portal veins and arteries express the Ang receptor Tie2 (a and b), and very low basal levels of Ang-2 (c and d). e and f: Tie2 levels increase in DT mice undergoing angiogenic remodeling, and are seen in hepatic veins and AV sprouts. g and h: Significant increases in Ang-2 levels are observed in DT mice and appear to occur in vessels undergoing angiogenic remodeling. Scale bar, 50 μm.
