Table 2.

Summary of Real-Time PCR Results and Histological Grading in AKR and C57BL/6 Mice Infected with E. muris

Day after infection	Spleen						Liver						Lungs
	Relative copies mean (SEM)*			Histological score† mean (SEM)			Relative copies mean (SEM)			Histological score mean (SEM)			Relative copies mean (SEM)			Histological score mean (SEM)
	AKR	C57BL/6	P‡	AKR	C57BL/6	P	AKR	C57BL/6	P	AKR	C57BL/6	P	AKR	C57BL/6	P	AKR	C57BL/6	P
4	366,279	18,334	0.03	2.8	2.5	0.51	24,971	12,498	0.2	1.3	1.5	0.5	45,356	359	0.03	3.5	1.0	0.03
	(77,547)	(6528)		(0.2)	(0.3)		(6274)	(4670)		(0.3)	(0.3)		(9728)	(155)		(0.5)	(0)
9	429,432	195,596	0.2	7.8	7.8	1.0	435,282	786,421	0.2	5.3	4.5	0.3	74,792	9243	0.001	7.5	8.3	0.4
	(154,436)	(42,503)		(0.5)	(0.3)		(169,258)	(145,103)		(0.6)	(0.3)		(7616)	(3918)		(0.6)	(0.5)
14	247,291	12,289	0.01	9.0	7.3	0.21	188,037	24,422	0.003	7.5	6.3	0.07	82,150	803	0.03	7.8	9.8	0.05
	(37,167)	(634)		(1.1)	(0.6)		(33,387)	(5022)		(0.3)	(0.5)		(21,464)	(207)		(0.6)	(0.5)
20	16,109	7535	0.26	7.0	7.0	1.0	4805	10,570	0.5	2.8	2.8	1.0	36,113	1097	0.004	6.0	5.8	0.81
	(6447)	(2511)		(0.6)	(0.4)		(1506)	(7891)		(0.5)	(0.3)		(7852)	(598)		(0.6)	(0.8)
30	3649	991	0.2	5.8	5.3	0.4	3213	3297	0.9	2.5	3.0	0.5	4977	239	0.03	3.5	7.3	0.003
	(1799)	(268)		(0.5)	(0.3)		(2507)	(1955)		(0.3)	(0.7)		(1292)	(44)	(0.6)	(0.5)

^*Units are expressed as relative amounts of ehrlichial DNA compared to the lowest amount of ehrlichial DNA present in the organs analyzed during the experiment. 

^†Spleen, 0 to 9; liver, 0 to 9; lungs, 0 to 12. SEM, standard error of the mean. 

^‡P values calculated by t-test or Mann-Whitney rank sum test where applicable.