Table 3.
Summary of Real-Time Results and Histological Grading in AKR and C57BL/6 Mice Infected with E. muris, Days 60 to 150 after Infection
| Day after infection | Spleen
|
Liver
|
Lungs
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Relative copies*
|
Histological score†
|
Relative copies
|
Histological score
|
Relative copies
|
Histological score
|
|||||||
| AKR | C57BL/6 | AKR | C57BL/6 | AKR | C57BL/6 | AKR | C57BL/6 | AKR | C57BL/6 | AKR | C57BL/6 | |
| 60 | 80 | 176 | 2.0 | 2.5 | 14 | 128 | 1.5 | 1.5 | 177 | 28 | 1.0 | 1.0 |
| 90 | 9 | 27 | 2.5 | 3.5 | 1 | 45 | 1.75 | 1.0 | 2 | 27 | 1.5 | 1.5 |
| 120 | 1 | 2.7 | 2.5 | 2.0 | 2 | 62 | 1.0 | 0.75 | 1 | 1 | 1.0 | 1.5 |
| 150 | ND | 1 | ND | 2.5 | ND | 1 | ND | 0.5 | ND | 2 | ND | 1.5 |
ND, Not done.
*
Units are expressed as relative amounts of ehrlichial DNA compared to the lowest amount of ehrlichial DNA present in the organs analyzed during the experiment. The value represents the average of two animals used at each time point. Therefore, SEM is not provided.
†
Spleen, 0 to 9; liver, 0 to 9; lungs, 0 to 12. The value represents the average of two animals used at each time point.