Table 1.

In Vivo and in Vitro Respiratory Activity of Pbx3-Deficient Mice

In vivo respiratory activity measured by plethysmography
Genotype	Frequency (per min)	Tidal volume (μl)	Minute volume (ml/min)
+/+ (n = 7)	124 ± 24	12.6 ± 4.5	1.57 ± 0.62
+/− (n = 9)	124 ± 38	11.8 ± 4.9	1.47 ± 0.91
−/− (n = 8)	81 ± 35*	9.0 ± 2.5	0.72 ± 0.29†

C4 inspiratory activity recorded in vitro
Genotype	Frequency (per min)	Duration (ms)	Amplitude (μV)
+/+ (n = 8)	6.0 ± 0.7	934 ± 371	246 ± 73
+/− (n = 15)	8.1 ± 1.4	958 ± 275‡	159 ± 52§
−/− (n = 11)	9.0 ± 2.1*	713 ± 239†	65 ± 35*

^*, p < 0.01 compared to +/+ and +/−.

^†, p < 0.05 compared to +/+ and +/−.

^‡, p < 0.05 compared to +/+.

^§, p < 0.01 compared to +/+.