Figure 7-4247.
Whole lung IL-4, IL-5, IL-13, TGF-β, IFN-γ, IL-12, and TNF-α at day 8 after S. mansoni egg infusion into S. mansoni-sensitized mice that received control IgG, anti-CCL17 antibody, or anti-CCL22 antibody. Whole lung samples were processed as described in the Materials and Methods section, and ELISA was used to determine specific cytokine levels in cell-free supernatants. Data are mean ± SEM of n = 5 per group. *, P ≤ 0.05 compared with chemokine levels detected in whole lung samples removed from the IgG control group at day 8 after S. mansoni egg embolizaton. τ, P ≤ 0.05 compared with cytokine levels detected in anti-CCL17 antibody-treated mice.