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H&E staining of lung sections obtained from mice 24 hours after the saline (a, b) or LPS (c, d) treatment. Saline-injected WT (a) and ORP150 TG (b) mice showed normal lung histology. LPS treatment resulted in diffuse alveolar wall injury and infiltration with inflammatory cells in WT mice (c), and these findings were attenuated in ORP150 TG mice (d). Original magnifications, ×200.
