Skip to main content
. 2004 Nov;165(5):1701–1718. doi: 10.1016/S0002-9440(10)63426-8

Figure 8.

Figure 8

Sections of spinal cords immunostained for Hsp25. First panel: 90-day-old mice transgenic for WT human SOD1 (WT) or the mutant G93A (G93A). Note weak neuronal cytoplasmic stain. Second panel: note stain in astrocytes in paralyzed mouse (G93A-par). The nontransgenic control (non-Tgn) shows Hsp25 in neuronal perikarya. Third panel: 30-day-old mouse, transgenic for G93A (30 days G93A) and from control expressing the WT (30 days WT) showing no difference in Hsp25 immunostain. Fourth and bottom panel: double immunolabeling for Hsp25 (HSP, green) and GFAP (red) shows Hsp25 accumulation of Hsp in reactive astrocytes. Original magnifications, ×200.